Big name fans are those who have attained a level of recognition within a fan community without necessarily knowing each participant in the subculture and who have the power to influence how other fans in their community engage with the object of their shared fandom.Their niche celebrity status can be achieved through the range of knowledge, access
T-joints are often used in large-scale welded constructions.The use of a laser beam for welding allows to create joints using various techniques.Used welding method affects the shape and size of heat affected zone, deformation of welded elements and consequently the quality of the joint.This work concerns the numerical modeling of the size of heat
Abstract Background Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease of the motor neuron system associated with both genetic and environmental risk factors.Infection with enteroviruses, including scalp serum poliovirus and coxsackievirus, such as coxsackievirus B3 (CVB3), has been proposed as a possible causal/risk factor fo
Tolvaptan is a highly selective vasopressin receptor 2 antagonist that regulates cyclic adenosine monophosphate levels to inhibit both epithelial cell proliferation and chloride ion excretion, two mechanisms known to induce cyst expansion in autosomal dominant polycystic kidney disease (ADPKD).Tolvaptan is currently the preferred treatment of rapid